Food and Drug Administration , were randomized, double-blind, controlled trials that enrolled a lot more than 1500 individuals with mild-to-moderate pain. Patients were assigned randomly, in a 2:1 ratio approximately, to receive either HZT-501 or the NSAID ibuprofen alone orally three times daily for a 24-week treatment period or until sufferers developed either an endoscopically diagnosed upper gastrointestinal ulcer and/or prohibitive toxicity. Results showed that patients with mild-to-moderate pain treated with HZT-501 developed around 50 % fewer NSAID-associated higher GI ulcers in comparison to patients treated with ibuprofen alone. The statistical analysis viewed the combined 1,382 individuals studied in the REDUCE-1 and REDUCE-2 primary study populations ————– – ——————– – Ibuprofen 2.18 Prior ulcer 1.65 Age group>’By identifying these independent risk factors, physicians might be able to better assess a patient’s risk for NSAID-associated GI toxicity,’ stated Timothy P.Glaucoma, the second leading cause of blindness in the global world, is a condition that occurs when an excessive amount of pressure builds up inside the eye. This surplus pressure pushes back against blood attempting to enter the attention resulting in vision loss. ‘Studies show that high blood pressure is a risk aspect for glaucoma. However the good reasons for this were never obvious,’ said writer Bang Bui, PhD, of the University of Melbourne, Australia, Department of Eyesight and Optometry Sciences. In the IOVS research, Chronic Hypertension Increases Susceptibility to Acute IOP Problem in Rats, Bang and his co-authors from the University of School and Melbourne of Medicine at Deakin University, Australia, identify a reason for those observations.