Among that cohort, the recommendation authors found strong proof that achieving sustained virologic response was associated with reduced risk for loss of life and liver cancer. The CDC recommends that individuals identified with HCV possess a brief alcohol intervention and screening, as alcohol use has been proven to accelerate the progression of liver disease. The recommendation authors considered evidence from a systematic review of 22 randomized, controlled trials released since 2010 to look for the effects of a short alcoholic beverages intervention versus no intervention on reduction of alcohol use. The study showed that patients who had a brief alcohol decrease intervention reduced their weekly alcohol consumption by typically 38.42 grams weighed against those that had no intervention.Blood transfusion therapy offers been shown to work in preventing overt strokes in individuals with sickle cell disease, but its efficiency and the willingness of family members to participate in long-term treatment to prevent silent strokes had not been tested. Sickle cell disease is an inherited bloodstream disorder affecting red bloodstream cells which contain hemoglobin, a chemical that bears oxygen from the new air in the lungs to all parts of the body.